Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].
体外研究 (In Vitro)
Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1]. The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay[1]
Cell Line:
U937 cells
Concentration:
0~80 μg/mL
Incubation Time:
96 hours
Result:
Showed cytotoxic activity in a dose-dependent pattern.
分子量
366.75
Formula
C17H15ClO7
CAS 号
643-84-5
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jin W H, et al. Cyanidin and Malvidin fromOryza sativacv. HeugjinjubyeoMediate Cytotoxicity against Human Monocytic Leukemia Cellsby Arrest of G2/M Phase and Induction of Apoptosis. J. Agric. Food Chem. 2004, 52, 8, 2213–2217
Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].
体外研究 (In Vitro)
Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1]. The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay[1]
Cell Line:
U937 cells
Concentration:
0~80 μg/mL
Incubation Time:
96 hours
Result:
Showed cytotoxic activity in a dose-dependent pattern.
分子量
366.75
Formula
C17H15ClO7
CAS 号
643-84-5
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jin W H, et al. Cyanidin and Malvidin fromOryza sativacv. HeugjinjubyeoMediate Cytotoxicity against Human Monocytic Leukemia Cellsby Arrest of G2/M Phase and Induction of Apoptosis. J. Agric. Food Chem. 2004, 52, 8, 2213–2217
Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].
体外研究 (In Vitro)
Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1]. The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].
上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay[1]
Cell Line:
U937 cells
Concentration:
0~80 μg/mL
Incubation Time:
96 hours
Result:
Showed cytotoxic activity in a dose-dependent pattern.
分子量
366.75
Formula
C17H15ClO7
CAS 号
643-84-5
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jin W H, et al. Cyanidin and Malvidin fromOryza sativacv. HeugjinjubyeoMediate Cytotoxicity against Human Monocytic Leukemia Cellsby Arrest of G2/M Phase and Induction of Apoptosis. J. Agric. Food Chem. 2004, 52, 8, 2213–2217
Malvidin-3-galactoside chloride Chemical Structure
CAS No. : 30113-37-2
规格
价格
是否有货
1 mg
￥3360
询问价格 & 货期
5 mg
￥10000
询问价格 & 货期
10 mg
￥15840
询问价格 & 货期
* Please select Quantity before adding items.
生物活性
Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function[1].
体外研究 (In Vitro)
Malvidin-3-galactoside chloride (50, 100, 200 μg/mL; for 24, 48, 72 h) displays obvious cytotoxicity on Huh-7 cells and has no significant effect with 50 and 100 μg/mL for 48 h. Malvidin-3-galactoside chloride has a notable cytotoxic effect against Huh-7 cells at 72 h[1]. Malvidin-3-galactoside chloride (50-200 μg/mL) arrests the cells in the S phase, accompanied by the cells in the G1 phase decreased, and the cells in the S phase increased[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) induces cell apoptosis in Huh-7 cells[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) markedly increased the levels of caspase-3, cleaved-caspase-3 and cleaved-PARP in a dose-dependent manner[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the production and accumulation of ROS[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) dramatically reduces the level of phosphorylation ERK (p-ERK) in a dose-dependent manner. Malvidin-3-galactoside chloride with 200 μg/mL markedly increases the phosphorylation level of p38 and JNK (p-p38 and p-JNK)[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the migration and invasion in Huh-7 cells[1].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
528.89
Formula
C23H25ClO12
CAS 号
30113-37-2
中文名称
氯化锦葵色素-3-O-半乳糖苷
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jie Lin, et al. Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways. Food Science and Human Wellness, Volume 9, Issue 2, June 2020, Pages 136-145.
Malvidin-3-galactoside chloride Chemical Structure
CAS No. : 30113-37-2
规格
价格
是否有货
1 mg
￥3360
询问价格 & 货期
5 mg
￥10000
询问价格 & 货期
10 mg
￥15840
询问价格 & 货期
* Please select Quantity before adding items.
生物活性
Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function[1].
体外研究 (In Vitro)
Malvidin-3-galactoside chloride (50, 100, 200 μg/mL; for 24, 48, 72 h) displays obvious cytotoxicity on Huh-7 cells and has no significant effect with 50 and 100 μg/mL for 48 h. Malvidin-3-galactoside chloride has a notable cytotoxic effect against Huh-7 cells at 72 h[1]. Malvidin-3-galactoside chloride (50-200 μg/mL) arrests the cells in the S phase, accompanied by the cells in the G1 phase decreased, and the cells in the S phase increased[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) induces cell apoptosis in Huh-7 cells[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) markedly increased the levels of caspase-3, cleaved-caspase-3 and cleaved-PARP in a dose-dependent manner[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the production and accumulation of ROS[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) dramatically reduces the level of phosphorylation ERK (p-ERK) in a dose-dependent manner. Malvidin-3-galactoside chloride with 200 μg/mL markedly increases the phosphorylation level of p38 and JNK (p-p38 and p-JNK)[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the migration and invasion in Huh-7 cells[1].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
528.89
Formula
C23H25ClO12
CAS 号
30113-37-2
中文名称
氯化锦葵色素-3-O-半乳糖苷
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jie Lin, et al. Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways. Food Science and Human Wellness, Volume 9, Issue 2, June 2020, Pages 136-145.
Malvidin-3-galactoside chloride Chemical Structure
CAS No. : 30113-37-2
规格
价格
是否有货
1 mg
￥3360
询问价格 & 货期
5 mg
￥10000
询问价格 & 货期
10 mg
￥15840
询问价格 & 货期
* Please select Quantity before adding items.
生物活性
Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function[1].
体外研究 (In Vitro)
Malvidin-3-galactoside chloride (50, 100, 200 μg/mL; for 24, 48, 72 h) displays obvious cytotoxicity on Huh-7 cells and has no significant effect with 50 and 100 μg/mL for 48 h. Malvidin-3-galactoside chloride has a notable cytotoxic effect against Huh-7 cells at 72 h[1]. Malvidin-3-galactoside chloride (50-200 μg/mL) arrests the cells in the S phase, accompanied by the cells in the G1 phase decreased, and the cells in the S phase increased[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) induces cell apoptosis in Huh-7 cells[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) markedly increased the levels of caspase-3, cleaved-caspase-3 and cleaved-PARP in a dose-dependent manner[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the production and accumulation of ROS[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) dramatically reduces the level of phosphorylation ERK (p-ERK) in a dose-dependent manner. Malvidin-3-galactoside chloride with 200 μg/mL markedly increases the phosphorylation level of p38 and JNK (p-p38 and p-JNK)[1]. Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the migration and invasion in Huh-7 cells[1].
上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
528.89
Formula
C23H25ClO12
CAS 号
30113-37-2
中文名称
氯化锦葵色素-3-O-半乳糖苷
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jie Lin, et al. Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways. Food Science and Human Wellness, Volume 9, Issue 2, June 2020, Pages 136-145.
