标签归档：monascin

Monascin(Synonyms: 红曲)

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Monascin (Synonyms: 红曲) 纯度: 98.93%

Monascin 是可从红曲米中提取得到的一种氮杂类色素，有口服活性，具有抗肿瘤和抗炎活性。Monascin 还能抑制NOR 的激活。

Monascin(Synonyms: 红曲)

Monascin Chemical Structure

CAS No. : 21516-68-7

规格 价格 是否有货 数量
5 mg ￥16500 In-stock
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Monascin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor)[1][2].

体内研究
(In Vivo)

Monascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter[1].
Dosage: 0.0025% in drinking water.
Administration: Orally daily for 2 weeks in drinking water.
Result: Reduced the number of the papillomas.

分子量

358.43

Formula

C21H26O5
CAS 号

21516-68-7
中文名称

红曲
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Akihisa T, et al. Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice). Chem Biodivers. 2005 Oct;2(10):1305-9.

    [2]. Lee CL, et al. Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent–monacolin K and antiinflammation agent–monascin. Appl Microbiol Biotechnol. 2006 Oct;72(6):1254-62.

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