Methotrexate PEG NHS, MW 2000 Cat. No. PG2-MXNS-2k 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methotrexate PEG NHS, MW 2000

Cat. No. PG2-MXNS-2k
Specification
Unit Size 5 mg
Price $485.00

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Synonym: Methotrexate PEG2000 NHS, NHS PEG Methotrexate, MTX PEG2000 NHS, NHS PEG MTX

Product Specifications:

  • Form: Solid;
  • Color: Yellow;
  • Functional groups: NHS;
  • Reactive to: Primary amine;
  • Solubility: Soluble in DMSO.

Storage Conditions:

  • Store at -20 0C. Protect from light.

4 Arm PEG NHS Cat. No. PG4A-NS-40k 40 kD 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

4 Arm PEG NHS

Cat. No. PG4A-NS-40k
Specification 40 kD
Unit Size 1 g
Price $385.00

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Product specifications:

  • Form: Solid;
  • Color: White;
  • PEG type: 4 branched PEG;
  • Reactive group: Succinimidyl ester (NHS);
  • Reactive to: Primary amine groups;
  • Purity: >95%.

Storage Conditions:

  • Store at -20 0C. Desiccate. 

NHS PEG2 Biotin, Biotin PEG2 NHS Cat. No. B-P2NS-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

NHS PEG2 Biotin, Biotin PEG2 NHS

Cat. No. B-P2NS-1 NHS PEG2 Biotin, Biotin PEG2 NHS           Cat. No. B-P2NS-1         5 mg
Specification
Unit Size 5 mg
Price $385.00

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Synonym: NHS PEG2 Biotin, Biotin PEG2 Succinimidyl ester, Biotin PEG2 NHS.

Description:

Biotin PEG2 NHS, also named NHS PEG2 Biotin, is one of Nanocs reactive PEG biotin reagents that have distinct PEG units. Biotin PEG2 NHS contains a 2 units ethylene glycol (-CH2CH2O-) between biotin and NHS (succinimidyl). NHS activated biotin can be used to label proteins, antibodies, small molecules or surfaces via their available amine groups. NHS reacts quickly with primary amine groups under alkaline pH to yield a stable amide bond. This reaction allows rapid attachement of biotin tag to targeted molecules or material surfaces. Resulted biotin tag can be easily detected with avidin or streptavidin. PEG linker between NHS and Biotin offers better water solubility, flexible linker structure and enhanced stability. 

Physical Properties:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in aqueous buffer
  • Reactive group: NHS (succinimidyl ester)
  • Reactive to: Primary amine group (-NH2)
  • PEG unis: two
  • Applications: Biotin conjugation (Biotinylation)
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.

References:

Click here to check hundreds publications using Nanocs PEGs.

Related Products
PG2-BNNS-5k-1 , Biotin-PEG-NHS, NHS PEG Biotin
PG2-BNNS-5k-2 , Biotin-PEG-NHS, NHS PEG Biotin
PG2-BNNS-3k , Biotin-PEG-NHS, NHS PEG Biotin
PG2-BNNS-2k , Biotin-PEG-NHS, NHS PEG Biotin

Biotin PEG400 NHS Cat. No. BN-NS-P400 10 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin PEG400 NHS

Cat. No. BN-NS-P400
Specification
Unit Size 10 mg
Price $385.00

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Synonym: NHS PEG400 Biotin

Description:

Biotin PEG400 NHS is one of Nanocs pegylated biotinylation reagents. Biotin PEG400 NHS enables simple and efficient biotin labeling of proteins, antibodies or other amine containing molecules or particles. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. N-hydroxysulfosuccinimide NHS esters of biotin react efficiently with primary amino groups (-NH2) in alkaline buffer to form a stable amide bond.

Specifications:

  • Appearance (color): Off-white;
  • Appearance (form): Semi-solid;
  • PEG length: PEG400, 8-10 PEG units;
  • Reactive group: NHS;
  • Reactive to: Primary amine group;
  • Solubility: Soluble in DMSO, DMF;
  • Application: Biotinylation.

Storage Conditions:

  • Store-20 0C. Desiccate. 

Biotin PEG4 NHS, NHS PEG4 Biotin Cat. No. B-P4NS-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin PEG4 NHS, NHS PEG4 Biotin

Cat. No. B-P4NS-1 Biotin PEG4 NHS, NHS PEG4 Biotin           Cat. No. B-P4NS-1         5 mg
Specification
Unit Size 5 mg
Price $385.00

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Synonym: NHS PEG4 Biotin, Biotin PEG4 Succinimidyl ester, Biotin PEG4 NHS.

Description:

Biotin PEG4 NHS, also named NHS PEG4 Biotin, is one of Nanocs reactive PEG biotin reagents that have distinct PEG units. Biotin PEG4 NHS contains 4 ethylene glycol (-CH2CH2O-)  units between biotin and NHS (succinimidyl). NHS activated biotin can be used to label proteins, antibodies, small molecules or surfaces via their available amine groups. NHS reacts quickly with primary amine groups under alkaline pH to yield a stable amide bond. This reaction allows rapid attachement of biotin tag to targeted molecules or material surfaces. Resulted biotin tag can be easily detected with avidin or streptavidin. PEG linker between NHS and Biotin offers better water solubility, flexible linker structure and enhanced stability. 

Physical Properties:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in aqueous buffer
  • Reactive group: NHS (succinimidyl ester)
  • Reactive to: Primary amine group (-NH2)
  • PEG unis: four
  • Applications: Biotin conjugation (Biotinylation)
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.

References:

Click here to check hundreds publications using Nanocs PEGs.

DOTA-PEG-NHS, MW 5000 Cat. No. PG2-DTNS-5k 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOTA-PEG-NHS, MW 5000

Cat. No. PG2-DTNS-5k
Specification
Unit Size 5 mg
Price $385.00

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Similar names: NHS PEG DOTA

Product information:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Reactive group: NHS ester
  • Reactive to: Primary amine (-NH2)
  • Reactive pH: 8-10
  • Application: Reactive metal chelator
  • Unit size: 5 mg

Storage:

  • Store at -20 0C. Protect from moisture.

DTPA PEG NHS, MW 5000 Cat. No. PG2-DANS-5k 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DTPA PEG NHS, MW 5000

Cat. No. PG2-DANS-5k
Specification
Unit Size 5 mg
Price $385.00

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Similar names: NHS PEG DTPA, DTPA PEG5000 NHS

Product information:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Reactive group: NHS ester
  • Reactive to: Primary amine (-NH2)
  • Reactive pH: 8-10
  • Application: Reactive metal chelator
  • Unit size: 5 mg

Storage:

  • Store at -20 0C. Protect from moisture.
Related Products
PG2-BNDTA-5k , DTPA PEG Biotin
PG2-DTAFC-5k , DTPA PEG FITC

Norbornene PEG NHS Cat. No. PG2-NBNS-5k 5000 Da 25 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Norbornene PEG NHS

Cat. No. PG2-NBNS-5k
Specification 5000 Da
Unit Size 25 mg
Price $325.00

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Synonym: NHS PEG Norbornene, Norbornene PEG5000 NHS, NHS PEG5000 Norbornene

Description:

Norbornene PEG NHS is one of Nanocs Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and a succinimidyl NHS group on the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, NHS group  allows conjugation of Norbornene group to various molecules via their amine groups. Resulted Norbornene group thus can participate various Click Chemistry reactions.  PEG linker between Norbornene and NHS offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive groups: Norbornene, NHS
  • Reactive to: Thiol, tetrazine, amine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Desiccate.
Related Products
PG4A-NB-10k , 4 arm Norbornene PEG

NHS activated Dextran Cat. No. DX40-NS-1 40 kDa 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

NHS activated Dextran

Cat. No. DX40-NS-1
Specification 40 kDa
Unit Size 5 mg
Price $425.00

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Similar names: Dextran NHS, Succinimidyl NHS Dextran

Description:

NHS activated dextran (Dextran-NHS) is  one of Nanocs chemical reactive dextran products that can react with primary amine groups under alkaline pH. NHS reacts rapidly with primary amine group at pH 8-10 to form a stable amide bond. NHS activated dextran can thus react rapidly with proteins, peptides or small molecules.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customized dextran products for your special needs.

Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: NHS
  • Reactive to: Primary amine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C. Protect  from moisture.
Related Products
DX40-AL-1 , Dextran, Aldehyde Functional
DX40-ML-1 , Dextran, Maleimide Functional
DX70-ML-1 , Dextran, Maleimide Functional
DX70-S5-1 , Dextran, Cy5 labeled

Dextran, NHS activated Cat. No. DX10-NS-1 10000 Da 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Dextran, NHS activated

Cat. No. DX10-NS-1
Specification 10000 Da
Unit Size 5 mg
Price $385.00

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Similar names: Dextran NHS, Succinimidyl NHS Dextran

Description:

NHS activated dextran (Dextran-NHS) is  one of Nanocs chemical reactive dextran products that can react with primary amine groups under alkaline pH. NHS reacts rapidly with primary amine group at pH 8-10 to form a stable amide bond. NHS activated dextran can thus react rapidly with proteins, peptides or small molecules.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customized dextran products for your special needs.

Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: NHS
  • Reactive to: Primary amine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C. Protect  from moisture.
Related Products
DX5-AL-1 , Dextran, Aldehyde Functional
DX10-AL-1 , Dextran, Aldehyde Functional
DX40-AL-1 , Dextran, Aldehyde Functional
DX70-AL-1 , Dextran, Aldehyde Functional
DX500-AL-1 , Dextran, Aldehyde Functional
DX2000-AL-1 , Dextran, Aldehyde Functional
DX3-AL-1 , Dextran, Aldehyde Functional
DX10-AM-1 , Dextran, Amine Functional
DX10-TH-1 , Dextran, Thiol Functional

Thiol PEG NHS, HS-PEG-NHS Cat. No. PG2-NSTH-1k 1000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG NHS, HS-PEG-NHS

Cat. No. PG2-NSTH-1k
Specification 1000 Da
Unit Size 100 mg
Price $485.00

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Synonym: HS PEG1000 NHS, HS-PEG-NHS, MW 1000, NHS-PEG-SH, MW 1000, Thiol PEG1000 NHS, NHS PEG1000 Thiol, NHS PEG1k HS, HS PEG1k NHS. Thiol PEG1k NHS, Sulfhydryl PEG NHS.

Product Specifications:

  • Appearance (form): Semi-solid;
  • Appearance (color): Off-whilte, pale yelllow:
  • Reactive groups: NHS ester and sulfhydryl (-SH);
  • Reactive to: Primary amine, gold surface;

Storage Conditions:

Store at -20 0C. Dessicate. 

Carbonylacrylic PEG NHS Cat. No. PG2-CRNS-5k 5000 Da 50 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Carbonylacrylic PEG NHS

Cat. No. PG2-CRNS-5k
Specification 5000 Da
Unit Size 50 mg
Price $385.00

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Synonym: NHS PEG Carbonylacrylic

Description:

Carbonylacrylic PEG NHS is a thiol and amine reactive heterobifunctional PEG derivatives. Similar to Maleimide, carbonylacrylic group can react with thiol group quickly to form a stable thiol ether bond. NHS, on the other hand, can react to primary amine group at alkaline pH to form a stable amide bond.

Product Specifications:

  • Form: Solid
  • Apearance: Light yellow/off-white
  • Reactive groups: Carbonylacrylic and NHS
  • Reactive to: Sulfhydryl and primary amine groups
  • Solubility: Soluble in water

Storage:

  • Store at -20 0C. Desiccate.

DSPE-NHS Cat. No. DS-NS-01 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE-NHS

Cat. No. DS-NS-01
Specification
Unit Size 5 mg
Price $385.00

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Synonym: NHS-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine-succinimidyl ester

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: NHS ester;
  • Reactive to: Primary amine group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-Maleimide, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

Biotin-PEG10-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Biotin-PEG10-NHS ester 

Biotin-PEG10-NHS ester 是一种 PROTAC linker,属于 PEG 类。Biotin-PEG10-NHS ester 可用于合成 PROTAC 分子。

Biotin-PEG10-NHS ester

Biotin-PEG10-NHS ester Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

852.99

Formula

C37H64N4O16S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Biotin-PEG10-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Biotin-PEG10-NHS ester 

Biotin-PEG10-NHS ester 是一种 PROTAC linker,属于 PEG 类。Biotin-PEG10-NHS ester 可用于合成 PROTAC 分子。

Biotin-PEG10-NHS ester

Biotin-PEG10-NHS ester Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

852.99

Formula

C37H64N4O16S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Biotin-PEG10-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Biotin-PEG10-NHS ester 

Biotin-PEG10-NHS ester 是一种 PROTAC linker,属于 PEG 类。Biotin-PEG10-NHS ester 可用于合成 PROTAC 分子。

Biotin-PEG10-NHS ester

Biotin-PEG10-NHS ester Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

852.99

Formula

C37H64N4O16S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DOPE NHS Cat. No. DO-NS-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOPE NHS

Cat. No. DO-NS-1
Specification
Unit Size 5 mg
Price $485.00

Qty Add to Cart

Synonym: NHS-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine NHS ester

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 un-saturated phospholipid;
  • Functional group: Maleimide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DOPE-Maleimide, DOPE-Biotin, DOPE-PEG, DOPE-FITC, DOPE-Pyrene

m-PEGn-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEGn-NHS ester 

m-PEGn-NHS ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

m-PEGn-NHS ester

m-PEGn-NHS ester Chemical Structure

CAS No. : 174569-25-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

(C2H4O)nC8H11NO5

CAS 号

174569-25-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

m-PEGn-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEGn-NHS ester 

m-PEGn-NHS ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

m-PEGn-NHS ester

m-PEGn-NHS ester Chemical Structure

CAS No. : 174569-25-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

(C2H4O)nC8H11NO5

CAS 号

174569-25-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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m-PEGn-NHS ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEGn-NHS ester 

m-PEGn-NHS ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

m-PEGn-NHS ester

m-PEGn-NHS ester Chemical Structure

CAS No. : 174569-25-6

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生物活性

m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

(C2H4O)nC8H11NO5

CAS 号

174569-25-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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