Paromomycin sulfate salt 硫酸盐
基本信息
| 产品名称 | Paromomycin sulfate salt 硫酸盐 |
|---|---|
| 英文名称 | Paromomycin sulfate salt |
| 规格或纯度 | 粉末，生物制剂，适用于细胞培养，≥98% |
| 生化机理 | Paromomycin possesses antileishmanial and antibacterial activities. It is used to cure visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL). This aminocyclitol glycoside is active against gram-negative and gram-positive bacteria. It is also active against E. histolytica , D. fragilis and several cestodes, like Taenia saginata , Taenia solium etc. Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death. |
一般描述
General Description
Chemical structure: aminoglycoside Paromomycin or aminosidine, an aminoglycoside belongs to the class of aminoglycosides. This nonabsorbable antibiotic is found at high level in the lumen of the colon.
Application
Paromomycin sulfate salt has been used as a: reference compound in antileishmanial activity RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex. Recommended for use in cell culture applications at 100mg/L. Paromomycin sulfate salt has been used as a positive control to compare the purine analog antiviral 2′,3′-dideoxyinosine (ddI).
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place 1g,5g
General Description
Chemical structure: aminoglycoside Paromomycin or aminosidine, an aminoglycoside belongs to the class of aminoglycosides. This nonabsorbable antibiotic is found at high level in the lumen of the colon.
Application
Paromomycin sulfate salt has been used as a: reference compound in antileishmanial activity RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex. Recommended for use in cell culture applications at 100mg/L. Paromomycin sulfate salt has been used as a positive control to compare the purine analog antiviral 2′,3′-dideoxyinosine (ddI).
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place 1g,5g
相关属性
| CAS编号 | 1263-89-4 |
|---|---|
| 比旋光度 | 48° (C=1,H2O) |
| 溶解性 | H2O：50mg/mL（在 2-8°C 下储存原液。在 37°C 下稳定 5 天。） |
| RTECS | WK2320000 |
| 分子式 | C23H45N5O14·xH2SO4 |
| 品牌 | Jinpan |
| PubChem CID | 441375 |