Phostriecin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Phostriecin 

Phostriecin 是一种由 Streptomyces pulveraceus 生产的抗肿瘤抗生素。 Phostriecin 是 2A 型 (PP2A) 的强抑制剂和 1 型 (PP1) 丝氨酸/苏氨酸蛋白磷酸酶的弱抑制剂,IC50< /sub>s 值分别为 3.2 nM 和 131 μM。Phostriecin 具有研究癌症的潜力。

Phostriecin

Phostriecin Chemical Structure

CAS No. : 131774-59-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Phostriecin is an antitumor antibiotic produced by Streptomyces pulveraceus. Phostriecin is a strong inhibitor of type 2A (PP2A) and a weak inhibitor of type 1 (PP1) serine/threonine protein phosphatases with IC50s of 3.2 nM and 131 μM, respectively. Phostriecin has the potential for the research of cancer[1].

分子量

491.51

Formula

C24H37NaO7P

CAS 号

131774-59-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Walsh AH, et al. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. FEBS Lett. 1997 Oct 27;416(3):230-4.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Phostriecin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Phostriecin 

Phostriecin 是一种由 Streptomyces pulveraceus 生产的抗肿瘤抗生素。 Phostriecin 是 2A 型 (PP2A) 的强抑制剂和 1 型 (PP1) 丝氨酸/苏氨酸蛋白磷酸酶的弱抑制剂,IC50< /sub>s 值分别为 3.2 nM 和 131 μM。Phostriecin 具有研究癌症的潜力。

Phostriecin

Phostriecin Chemical Structure

CAS No. : 131774-59-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Phostriecin is an antitumor antibiotic produced by Streptomyces pulveraceus. Phostriecin is a strong inhibitor of type 2A (PP2A) and a weak inhibitor of type 1 (PP1) serine/threonine protein phosphatases with IC50s of 3.2 nM and 131 μM, respectively. Phostriecin has the potential for the research of cancer[1].

分子量

491.51

Formula

C24H37NaO7P

CAS 号

131774-59-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Walsh AH, et al. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. FEBS Lett. 1997 Oct 27;416(3):230-4.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务