标签归档：reductase

Aldose reductase-IN-4

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aldose reductase-IN-4 

Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶 (aldose reductase) 抑制剂，对醛还原酶 1 (ALR1) 和 ALR2 的 IC50 分别为 11.70 μM 和 0.98 μM。

Aldose reductase-IN-4

Aldose reductase-IN-4 Chemical Structure

CAS No. : 2446136-17-8

规格 是否有货
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生物活性

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

IC50 & Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]
分子量

291.30

Formula

C14H10FNO3S
CAS 号

2446136-17-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

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Aldose reductase-IN-4

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aldose reductase-IN-4 

Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶 (aldose reductase) 抑制剂，对醛还原酶 1 (ALR1) 和 ALR2 的 IC50 分别为 11.70 μM 和 0.98 μM。

Aldose reductase-IN-4

Aldose reductase-IN-4 Chemical Structure

CAS No. : 2446136-17-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

IC50 & Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]
分子量

291.30

Formula

C14H10FNO3S
CAS 号

2446136-17-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aldose reductase-IN-4

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aldose reductase-IN-4 

Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶 (aldose reductase) 抑制剂，对醛还原酶 1 (ALR1) 和 ALR2 的 IC50 分别为 11.70 μM 和 0.98 μM。

Aldose reductase-IN-4

Aldose reductase-IN-4 Chemical Structure

CAS No. : 2446136-17-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

IC50 & Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]
分子量

291.30

Formula

C14H10FNO3S
CAS 号

2446136-17-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Thioredoxin reductase peptide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Thioredoxin reductase peptide 

Thioredoxin reductase peptide 是硫氧还蛋白还原酶的 53–67 残基对应的多肽，用于硫氧还蛋白还原酶研究。硫氧还蛋白还原酶作为含二硫化物蛋白质的还原剂，在细胞抗氧化防御中起着重要作用。

Thioredoxin reductase peptide

Thioredoxin reductase peptide Chemical Structure

CAS No. : 950890-23-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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Thioredoxin reductase peptide 的其他形式现货产品:

Thioredoxin reductase peptide TFA

生物活性

Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].

分子量

1503.79

Formula

C66H106N18O18S2
CAS 号

950890-23-0
Sequence

Trp-Gly-Leu-Gly-Gly-Thr-Cys-Val-Asn-Val-Gly-Cys-Ile-Pro-Lys
Sequence Shortening

WGLGGTCVNVGCIPK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jan YH, et al. Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine(methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. Chem Res Toxicol. 2014 Jan 21;27(1):61-75.

    [2]. Valette O, et al. Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase from Desulfovibrio vulgaris. Front Microbiol. 2017 Sep 29;8:1855.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务