上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
SBP-0636457 (Synonyms: SBI-0636457; SB1-0636457) 纯度: 98.42%
SBP-0636457 (SB1-0636457) 是一种 SMAC 模拟物,是 IAP 的拮抗剂。SBP-0636457 以 0.27 μM 的 Ki 与 IAP 蛋白的 BIR 结构域结合。SBP-0636457 可用于实体瘤和血液系统癌症的研究。
SBP-0636457 Chemical Structure
CAS No. : 1422180-49-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥12000 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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SBP-0636457 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
生物活性 |
SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
SBP-0636457 (1-20 μM) demonstrates no cytotoxicity in BT474, BT549, MCF7, and MDA-MB-231 breast cancer cell lines up to a concentration of 20μM[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
456.58 |
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Formula |
C25H36N4O4 |
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CAS 号 |
1422180-49-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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参考文献 |
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