SPOP-IN-6b dihydrochloride

发表于2024年9月29日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SPOP-IN-6b dihydrochloride 纯度: 99.90%

SPOP-IN-6b dihydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC₅₀ 为 3.58 μM。

SPOP-IN-6b dihydrochloride Chemical Structure

规格	价格	是否有货
5 mg	￥2500	In-stock
10 mg	￥4200	In-stock
25 mg	￥8900	In-stock
50 mg	￥15000	In-stock
100 mg		询价
200 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b dihydrochloride 相关产品

•相关化合物库:

Bioactive Compound Library Plus
Anti-Cancer Compound Library

生物活性

SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM^[1].

体外研究
(In Vitro)

SPOP-IN-6b dihydrochloride shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells^[1].
SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

573.51

Formula

C₂₈H₃₄Cl₂N₆O₃

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

DMSO : 41.67 mg/mL (72.66 mM; ultrasonic and warming and heat to 60°C)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.7436 mL	8.7182 mL	17.4365 mL
5 mM	0.3487 mL	1.7436 mL	3.4873 mL
10 mM	0.1744 mL	0.8718 mL	1.7436 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.08 mg/mL (3.63 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (3.63 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。

参考文献

[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

生物活性分子抑制剂SPOP-IN-6b

发表于2024年4月8日由上海金畔生物科技有限公司

SPOP-IN-6b 纯度: 99.61%

SPOP-IN-6b 是一种 SPOP 抑制剂，IC₅₀ 为 3.58 μM (来自专利 CN 107141287，化合物 SPOP-B-88)。

SPOP-IN-6b Chemical Structure

CAS No. : 2136270-20-5

规格	价格	是否有货
10 mM * 1 mL in DMSO	￥3850	In-stock
5 mg	￥3500	In-stock
10 mg	￥5500	In-stock
50 mg	￥16500	In-stock
100 mg	￥22500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b 相关产品

•相关化合物库:

Bioactive Compound Library Plus
Anti-Cancer Compound Library
Targeted Diversity Library

生物活性

SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM (patent CN 107141287, SPOP-B-88)^[1].

IC₅₀ & Target

SPOP^[1]

体外研究
(In Vitro)

SPOP-IN-6b shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells^[1].
SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

SPOP-IN-6b (40-80 mg/kg; i.p.; daily; for 25 days) can slow down the growth of tumour by suppressing SPOP^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Nude mice^[1]
Dosage:	40 mg/kg, 60 mg/kg, 80 mg/kg
Administration:	Intraperitoneal injection; daily; for 25 days
Result:	Slowed down the growth of tumour by suppressing SPOP.

分子量

500.59

Formula

C₂₈H₃₂N₆O₃

CAS 号

2136270-20-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 10 mg/mL (19.98 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.9976 mL	9.9882 mL	19.9764 mL
5 mM	0.3995 mL	1.9976 mL	3.9953 mL
10 mM	0.1998 mL	0.9988 mL	1.9976 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 1 mg/mL (2.00 mM); Clear solution

此方案可获得 ≥ 1 mg/mL (2.00 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 10.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1 mg/mL (2.00 mM); Clear solution

此方案可获得 ≥ 1 mg/mL (2.00 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 10.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

生物活性分子抑制剂SPOP-IN-6b

发表于2024年4月8日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
SPOP-IN-6b 纯度: 99.61%

SPOP-IN-6b 是一种 SPOP 抑制剂，IC₅₀ 为 3.58 μM (来自专利 CN 107141287，化合物 SPOP-B-88)。

SPOP-IN-6b Chemical Structure

CAS No. : 2136270-20-5

规格	价格	是否有货
10 mM * 1 mL in DMSO	￥3850	In-stock
5 mg	￥3500	In-stock
10 mg	￥5500	In-stock
50 mg	￥16500	In-stock
100 mg	￥22500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b 相关产品

•相关化合物库:

Bioactive Compound Library Plus
Anti-Cancer Compound Library
Targeted Diversity Library

生物活性

SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM (patent CN 107141287, SPOP-B-88)^[1].

IC₅₀ & Target

SPOP^[1]

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

SPOP-IN-6b (40-80 mg/kg; i.p.; daily; for 25 days) can slow down the growth of tumour by suppressing SPOP^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Nude mice^[1]
Dosage:	40 mg/kg, 60 mg/kg, 80 mg/kg
Administration:	Intraperitoneal injection; daily; for 25 days
Result:	Slowed down the growth of tumour by suppressing SPOP.

分子量

500.59

Formula

C₂₈H₃₂N₆O₃

CAS 号

2136270-20-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 10 mg/mL (19.98 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.9976 mL	9.9882 mL	19.9764 mL
5 mM	0.3995 mL	1.9976 mL	3.9953 mL
10 mM	0.1998 mL	0.9988 mL	1.9976 mL

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 1 mg/mL (2.00 mM); Clear solution

此方案可获得 ≥ 1 mg/mL (2.00 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 10.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1 mg/mL (2.00 mM); Clear solution

此方案可获得 ≥ 1 mg/mL (2.00 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 10.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPOP-IN-6b hydrochloride

发表于2023年12月24日由上海金畔生物科技有限公司

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC₅₀ 为 3.58 μM。

SPOP-IN-6b hydrochloride Chemical Structure

CAS No. : 2136270-68-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b hydrochloride 的其他形式现货产品:

SPOP-IN-6b SPOP-IN-6b dihydrochloride

生物活性	SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM^[1].
体外研究 (In Vitro)	SPOP-IN-6b shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells^[1]. SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	537.05
Formula	C₂₈H₃₃ClN₆O₃
CAS 号	2136270-68-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPOP-IN-6b hydrochloride

发表于2023年12月24日由上海金畔生物科技有限公司

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC₅₀ 为 3.58 μM。

SPOP-IN-6b hydrochloride Chemical Structure

CAS No. : 2136270-68-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b hydrochloride 的其他形式现货产品:

SPOP-IN-6b SPOP-IN-6b dihydrochloride

生物活性	SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM^[1].
体外研究 (In Vitro)	SPOP-IN-6b shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells^[1]. SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	537.05
Formula	C₂₈H₃₃ClN₆O₃
CAS 号	2136270-68-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPOP-IN-6b hydrochloride

发表于2023年12月23日由上海金畔生物科技有限公司

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC₅₀ 为 3.58 μM。

SPOP-IN-6b hydrochloride Chemical Structure

CAS No. : 2136270-68-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

SPOP-IN-6b hydrochloride 的其他形式现货产品:

SPOP-IN-6b SPOP-IN-6b dihydrochloride

生物活性	SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM^[1].
体外研究 (In Vitro)	SPOP-IN-6b shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells^[1]. SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	537.05
Formula	C₂₈H₃₃ClN₆O₃
CAS 号	2136270-68-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

whatman (沃特曼)

英国沃特曼 Millipore PALL中国代理商金畔官网

标签归档：spop

SPOP-IN-6b dihydrochloride

SPOP-IN-6b dihydrochloride 相关产品

•相关化合物库:

生物活性分子抑制剂SPOP-IN-6b

SPOP-IN-6b 相关产品

•相关化合物库:

生物活性分子抑制剂SPOP-IN-6b

SPOP-IN-6b 相关产品

•相关化合物库:

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride

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