STM2457 纯度: 99.89%
STM2457 是一种首创的,高效、选择性的,具有口服活性的 METTL3 抑制剂,其 IC50 为 16.9 nM.,可用于急性白血病的研究。
STM2457 Chemical Structure
CAS No. : 2499663-01-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥2080 | In-stock | |
10 mg | ¥3520 | In-stock | |
25 mg | ¥6800 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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STM2457 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Anti-Cancer Compound Library
- Orally Active Compound Library
- Chemical Probe Library
- Targeted Diversity Library
生物活性 |
STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2]. |
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体外研究 (In Vitro) |
STM2457 (Compound 72) inhibits MOLM13 cells proliferation with an IC50 of 8.699 μM[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
444.53 |
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Formula |
C25H28N6O2 |
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CAS 号 |
2499663-01-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (112.48 mM; ultrasonic and warming and heat to 60°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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