上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
CBK289001
CBK289001 是一种抗酒石酸酸性磷酸酶 (TRAP/ACP5) 抑制剂。CBK289001 抑制 TRAP 5bMV,TRAP 5bOX 和 TRAP 5aOX,IC50 分别为 125 µM,4.21 µM 和 14.2 µM。
CBK289001 Chemical Structure
CAS No. : 1212663-24-5
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100 mg |
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250 mg |
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500 mg |
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生物活性 |
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively[1].
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体外研究 (In Vitro) |
Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 µM or 100 µM[1]. CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells[1].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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