硫酸博来霉素 来源于轮枝链霉菌
BioReagent Plus,水晶
有货
基本信息
产品名称 | 硫酸博来霉素 来源于轮枝链霉菌 |
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英文名称 | Bleomycin sulfate from Streptomyces verticillus |
别名 | Bleo, Blenoxane, Blexane |
英文别名 | Bleo, Blenoxane, Blexane |
规格或纯度 | BioReagent Plus,水晶 |
运输条件 | 冰袋运输 |
生化机理 | Bleomycin sulfate binds to DNA, causes ssDNA scission at specific base sequences and inhibits DNA synthesis. This inhibitory action requires bleomycin to bind oxygen and a metal ion. It can also cleave RNA, to a lesser degree but more selectively. It acts as an inducer and regulator of apoptosis and inhibits tumor angiogenesis. |
一般描述
制备说明
The product is soluble in water in water at 20 mg/mL and is active for several days. A solution of 2 units/mL in 0.1 M neutral potassium phosphate should be used within 14 days. A solution is active for three months at 3 units/mL in normal saline.
General Description
Chemical structure: glycopeptide
Application
Bleomycin Sulfate is an antineoplastic antibiotic isolated from Streptomyces verticillus. It is recommended for use as a cell culture agent at 10-100 μg/mL.
Other Notes
Keep container tightly closed in a dry and well-ventilated place, strongly hygroscopic
相关属性
CAS编号 | 9041-93-4 |
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溶解性 | H2O:20mg/mL,透明,无色 |
储存温度 | 2-8°C储存 |
RTECS | EC5991990 |
分子量 | 1512.62 |
分子式 | C55H84N17O21S3·HSO4 |
EC号 | 232-925-2 |
品牌 | Jinpan |
备注 | 注意: This product should be stored at Store at 2-8°C. |
PubChem CID | 122172957 |