(S,R,S)-AHPC-C6-NH2 hydrochloride(Synonyms: VH032-C6-NH2 hydrochloride)

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(S,R,S)-AHPC-C6-NH2 hydrochloride (Synonyms: VH032-C6-NH2 hydrochloride)

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 VH032 的 VHL 配体和 1 个 linker。(S,R,S)-AHPC-C6-NH2 hydrochloride 可用于合成靶向 AKT的 PROTAC 降解剂，例 6，XF038-161A，源于专利文献 WO2019173516A1。

(S,R,S)-AHPC-C6-NH2 hydrochloride(Synonyms: VH032-C6-NH2 hydrochloride)

(S,R,S)-AHPC-C6-NH2 hydrochloride Chemical Structure

CAS No. : 2360522-76-3

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(S,R,S)-AHPC-C6-NH2 hydrochloride 的其他形式现货产品:

(S,R,S)-AHPC-C6-NH2

生物活性

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].

IC50 & Target

VHL

 

体外研究
(In Vitro)

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C5-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader, XF038-161A, example 6, extracted from patent WO2019173516A1[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

594.21

Formula

C29H44ClN5O4S
CAS 号

2360522-76-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

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