上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Aurora inhibitor 1
Aurora inhibitor 1 是一种有效的 Aurora 抑制剂，抑制 Aurora A 和 Aurora B 激酶的 IC50 分别 ≤4 nM 和 ≤13 nM。
Aurora inhibitor 1 Chemical Structure
CAS No. : 2227019-45-4
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| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively[1]. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01 nM for both Aurora A and Aurora B kinase[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
459.57 |
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| Formula |
C23H25N9S |
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| CAS 号 |
2227019-45-4 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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