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HE-S2
HE-S2 是一种抗体偶联药物，可触发有效的抗肿瘤免疫反应。HE-S2 通过阻断 PD-1/PD-L1 的相互作用，激活 Toll 样受体 7/8 (TLR7/8) 信号通路发挥作用。HE-S2 具有显著的抗肿瘤活性。
HE-S2 Chemical Structure
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity[1]. |
IC50 & Target |
PD-1/PD-L1 and TLR7/8 [1] |
|---|---|
| 体外研究 (In Vitro) |
HE-S2 (10 ng; 30 min) effectively targets and binds with PD-L1in MC38 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
787.95 |
| Formula |
C38H45N9O6S2 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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