上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
TNIK-IN-5
TNIK-IN-5 是一种高效的 TNIK 抑制剂,IC50 为 0.05 μM。TNIK-IN-5 能有效抑制完整细胞的 Wnt 信号通路。TNIK-IN-5 具有良好的体外抗结直肠癌活性。
TNIK-IN-5 Chemical Structure
CAS No. : 2754265-66-0
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生物活性 |
TNIK-IN-5 is an efficient TNIK inhibitor with IC50 of 0.05 μM. TNIK-IN-5 efficiently inhibits Wnt signaling in intact cells. TNIK-IN-5 shows excellent in vitro anti-colorectal cancer activity[1]. |
IC50 & Target |
IC50: 0.05 μM (TNIK)[1] |
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体外研究 (In Vitro) |
TNIK-IN-5 (compound 8g) (1.25-5 μM; 48 hours) significantly inhibits the cell proliferation of HCT116 in a dose-dependent manner[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation Assay
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分子量 |
371.39 |
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Formula |
C22H17N3O3 |
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CAS 号 |
2754265-66-0 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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