Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity^[1][2].

Globosuxanthone A shows cytotoxicities against NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, DU-145 cells (IC₅₀=0.65-3.6 µM)^[1].
Globosuxanthone A impairs cell cycle progression of NCI-H460 and PC-3M cells leading to accumulation in the G2/M and S phases ^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

304.25

C₁₅H₁₂O₇

917091-74-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Miao C, et al. Antifungal xanthones produced by the endophytic fungus Paraconionthyrium sp. YM 311593. Folia Microbiol (Praha). 2020;65(3):567-572.

  [2]. Wijeratne EM, et al. A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity. Bioorg Med Chem. 2006;14(23):7917-7923.