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Galloflavin
Galloflavin 是一种有效的乳酸脱氢酶 (LDH) 抑制剂。通过 Pyruvate 的计算 Ki 为 5.46 µM (LDH-A) 和15.06 µM (LDH-B)。Galloflavin 通过阻断糖酵解和 ATP 的产生而阻碍癌细胞的增殖。
Galloflavin Chemical Structure
CAS No. : 568-80-9
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥1000 | In-stock | |
10 mg | ¥1600 | In-stock | |
50 mg | ¥5600 | In-stock | |
100 mg | ¥9500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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Galloflavin 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Anti-Cancer Compound Library
- Glycolysis Compound Library
- Anti-Cancer Metabolism Compound Library
- Glucose Metabolism Compound Library
生物活性 |
Galloflavin is a potent lactate dehydrogenase (LDH) inhibitor. The calculated Kis for pyruvate are 5.46 µM (LDH-A) and 15.06 µM (LDH-B). Galloflavin hinders the proliferation of cancer cells by blocking glycolysis and ATP production[1][2]. |
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体外研究 (In Vitro) |
Galloflavin effectively inhibits cell growth in endometrial cancer cell lines and primary cultures of human endometrial cancer through its involvement in multiple signaling pathways that regulate metabolism, cell cycle, apoptosis, cell stress and metastasis[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
278.17 |
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Formula |
C12H6O8 |
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CAS 号 |
568-80-9 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 8.33 mg/mL (29.95 mM; ultrasonic and warming and heat to 80°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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