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NCX4040 (Synonyms: NO-Aspirin)
NCX4040 (NO-Aspirin) 是一种非甾体抗炎药 (NSAID),是一种一氧化氮 (NO) 释放形式的 Aspirin。NCX4040 在 PC3 转移性前列腺癌细胞中诱导细胞凋亡 (apoptosis)。NCX4040 具有抗炎和抗癌作用。
NCX4040 Chemical Structure
CAS No. : 287118-97-2
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100 mg | 询价 | ||
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生物活性 |
NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects[1]. |
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体外研究 (In Vitro) |
NCX4040 significantly induces hydrogen peroxide formation with ensuing oxidative stress and mitochondrial depolarization resulting in lipid peroxidation, cell cycle arrest, inhibition of colony growth and induction of apoptosis in PC3 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
331.28 |
Formula |
C16H13NO7 |
CAS 号 |
287118-97-2 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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