CSF1R-IN-4

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

CSF1R-IN-4 

CSF1R-IN-4 是一种有效的 CSF1R 抑制剂。CSF-1R在巨噬细胞中表达,巨噬细胞的存活和分化依赖于CSF-1/CSF-1R信号通路。CSF1R-IN-4 影响 TAM 和胶质瘤细胞之间炎症因子的交换。CSF1R-IN-4 具有研究癌症疾病的潜力 (信息提取自专利 WO2021197276A1, 化合物 104)。

CSF1R-IN-4

CSF1R-IN-4 Chemical Structure

CAS No. : 2716185-86-1

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生物活性

CSF1R-IN-4 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104)[1].

分子量

428.44

Formula

C23H20N6O3

CAS 号

2716185-86-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.

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