(E/Z)-Zotiraciclib hydrochloride(Synonyms: (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride)

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(E/Z)-Zotiraciclib hydrochloride (Synonyms: (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride)

(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride 是一种有效的 CDK2JAK2FLT3 抑制剂,用于癌症研究。

(E/Z)-Zotiraciclib hydrochloride(Synonyms: (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride)

(E/Z)-Zotiraciclib hydrochloride Chemical Structure

CAS No. : 1321626-25-8

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(E/Z)-Zotiraciclib hydrochloride 相关产品

相关化合物库:

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生物活性

(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent CDK2, JAK2, and FLT3 inhibitor[1].

IC50 & Target[1]

CDK2

 

JAK2

 

FLT3

 

分子量

408.92

Formula

C23H25ClN4O

CAS 号

1321626-25-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献
  • [1]. William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer. J Med Chem. 2012;55(1):169-196.

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