CDK7-IN-7

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

CDK7-IN-7 

CDK7-IN-7 是一种有效的 CDK7 抑制剂,IC50 为 <50 nM. 详细信息可参考专利 CN112661745A, compound T-01。

CDK7-IN-7

CDK7-IN-7 Chemical Structure

CAS No. : 2640208-01-9

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生物活性

CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nm (patent cn112661745a, compound t-01)[1].

IC50 & Target[1]

CDK7

<50 nM (IC50)

体外研究
(In Vitro)

CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

513.31

Formula

C20H20BrF3N6O2

CAS 号

2640208-01-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Compounds useful as CDK7 kinase inhibitors and uses thereof. CN112661745A.

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