Ftase inhibitor I(Synonyms: B581)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ftase inhibitor I (Synonyms: B581)

Ftase inhibitor I (B581) 是一种有效的，选择性的拟肽法尼基转移酶 FTase 抑制剂。Ftase inhibitor I 对 FTase 的选择性优于香叶基香叶基类异戊二烯 (Ras-GG) 或脂肪酸肉豆蔻酸酯 (Myr-Ras)

Ftase inhibitor I(Synonyms: B581)

Ftase inhibitor I Chemical Structure

CAS No. : 149759-96-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)[1].

体外研究
(In Vitro)

Ftase inhibitor I (B581) inhibits the ability of only Ras-F-transformed cells, but not geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)- (or Raf-) transformed cells, to grow in soft agar[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

470.69

Formula

C22H38N4O3S2
CAS 号

149759-96-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. A D Cox, et al. The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. J Biol Chem. 1994 Jul 29;269(30):19203-6.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

发表回复