PIM1-IN-4

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

PIM1-IN-4 

PIM1-IN-4 (Compound 8) 是一种有效的 PIM1 抑制剂。PIM1-IN-4 显示对其他五种酶的强抑制作用,即 SGK-1、PKA、CaMK-1、GSK3β 和 MSK1。PIM1-IN-4 具有研究癌症疾病的潜力。

PIM1-IN-4

PIM1-IN-4 Chemical Structure

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生物活性

PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM1-IN-4 has the potential for the research of cancer diseases[1].

分子量

663.88

Formula

C27H25BrCl2CuN6O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wittmann C, et al. Highly Antiproliferative Latonduine and Indolo[2,3-c]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. J Med Chem. 2022 Feb 10;65(3):2238-2261.

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