ALDH3A1-IN-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ALDH3A1-IN-1 

ALDH3A1-IN-1 (Compound 18) 是一种有效的 ALDH3A1 抑制剂,IC50 为 1.61 μM。ALDH3A1-IN-1 作为单药或与多西紫杉醇联合治疗,对患者来源的原发性前列腺肿瘤上皮细胞比 DEAB 更有效。

ALDH3A1-IN-1

ALDH3A1-IN-1 Chemical Structure

CAS No. : 1039855-56-5

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生物活性

ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination treatment with docetaxel[1].

分子量

250.29

Formula

C13H18N2O3

CAS 号

1039855-56-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

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