上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Anticancer agent 65
Anticancer agent 65 (化合物 4c) 在肿瘤细胞系中表现出良好的活性，尤其是 A549 细胞，其 IC50 为 1.07 μM。Anticancer agent 65 诱导 A549 细胞 S 期阻滞，提高 p53、p21 的表达水平。Anticancer agent 65 引起 A549 细胞凋亡，ROS 生成和 MMP 崩溃。
Anticancer agent 65 Chemical Structure
CAS No. : 2407861-48-5
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells[1]. |
|||
|---|---|---|---|---|
| IC50 & Target |
|
|||
| 体外研究 (In Vitro) |
Anticancer agent 65 (compound 4c) increases the expression of Bax and decrease that of Bcl-2[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
|||
| 分子量 |
589.89 |
|||
| Formula |
C36H63NO5 |
|||
| CAS 号 |
2407861-48-5 |
|||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
|||
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
|||
| 参考文献 |
|
所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务